Hy ! I'm french (sorry for my english)
Before install JMS on a final website, i'want to test it on a webdev site, and i'v install a J-1.5.9 in a sub folder (
www.mydomain.com/jmultisites) and when i'want create a slive site, i've test lot of url param :
slive name : demo
- 
www.mydomain.com/jmultisites/demo
- 
www.mydomain.com/demo.jmultisites
- 
demo.jmultisites.mydomain.com
 for exemple, but that not ok !!!
if i've give the same directory 
www.mydomain.com/jmultisites
www.mydomain.com/jmultisites, evidence, the J-install taking hand, and i can't use mys master website...
then, it is possible to use in a site installing in a sub folder, or it's necessary to install it in a real website with only 
www.ydomain.com 
thank's